Awarded the World’s Most Effective Depigmentation Treatment
Cosmelan by Mesoestetic is a clinical depigmentation method which has an intensive corrective effect on hyperpigmentation, whilst regulating the overproduction of melanin in the melanocytes, inhibiting and controlling the appearance of new dark spots. This treatment works by a dual action-based approach:
Cosmelan works at two levels: At the first level by inhibiting the activation of tyrosinase inside the melanosome, reducing the oxidative stress, and thereby reducing melanin synthesis. Then at a second level, by containing copper chelators (Cu2+) tyrosinase function is reduced. Cosmelan acts by blocking the transfer of the melanosome to the keratinocytes, thereby preventing movement of the pigment to the superficial layers of the skin.
The cosmelan peel reduces the amount of melanin synthesised, reducing the intensity of the dark spot. It also acts on the stratum corneum, stimulating the renewal of the epidermis and intensively eliminating the accumulation of melanin.